Review: Betadine Vaginal (Povidone-Iodine)

Betadine Vaginal Preparations is a povidone-iodine mixture specifically formulated for vaginal use, either in a gel, douche or suppository.

Betadine is known to be bactericidal, trichomonacidal, virucidal and fungicidal. That means it kills bacteria, trichomonas, viruses and fungi, including yeasts.

Learn how to use povidone-iodine (Betadine) vaginally

Betadine is water soluble, creating a brown liquid, and unlike iodine, does not tend to stain skin or fabrics, though it is advisable to wear a panty liner as some staining may occur with synthetic fabric. The iodine in the mixture is the antiseptic element.

What Betadine Vaginal Preparations may treat

  • Vaginal infections
  • Non-specific vaginitis
  • Vaginitis
  • Vulvovaginitis associated with Trichomonas vaginalis and monilial infection

Instructions for use and safety

  • Only use as a douche if that is the formulation – do not drink
  • Do not use if you are sensitive to iodine
  • Do not use in cases of sexually transmitted infection or pelvic inflammatory disease – see your doctor
  • If symptoms persist after five days of use, or redness or pain develops, stop using the product and see your doctor
  • Betadine is spermicidal, so if you are trying to get pregnant, avoid during fertile periods
  • Do not use during pregnancy or while breastfeeding – vaginal absorption of iodine does occur

Preparations, treatments and doses


  • 5g application and dose
  • Mahogany coloured gel
  • Contains povidone-iodine USP 10 per cent (1 per cent available iodine) in diffusible, water soluble polyethylene glycols
  • pH 3.5 – 4.5
  • Tube 85g with applicator


  • One suppository is one dose
  • Contains povidone-iodine USP 200mg (20mg available iodine) in polyethylene glycol base
  • Package contains 14 with applicator


  • Betadine Concentration 25ml in 1 litre of lukewarm water per dose for infection, continue for up to two weeks, including during menstruation
  • Routine douche (which is not recommended) – 6-12 ml in 1 litre of warm water no more than once or twice per week
  • Scented formula
  • Contains povidone-iodine USP 10 per cent (1 per cent available iodine)
  • pH diluted 3.0 – 3.5
  • Douching apparatus purchased separatedly
  • Bottles of 100ml and 250ml
  • Protect from excessive heat

Jessica Lloyd - Vulvovaginal Specialist Naturopathic Practitioner, BHSc(N)

Jessica is a degree-qualified naturopath (BHSc) specialising in vulvovaginal health and disease, based in Melbourne, Australia.

Jessica is the owner and lead naturopath of My Vagina, and is a member of the:

  • International Society for the Study of Vulvovaginal Disease (ISSVD)
  • International Society for the Study of Women's Sexual Health (ISSWSH)
  • National Vulvodynia Association (NVA) Australia
  • New Zealand Vulvovaginal Society (ANZVS)
  • Australian Traditional Medicine Society (ATMS)