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Infection of Candida glabrata is becoming more common, with antifungal drug resistance. Like all vulvovaginal yeast infections, a Candida glabrata infection in the vulvovaginal region is a result of yeast overgrowth from the gut. Accordingly, to prevent recurrence, the gut must be treated while also killing the infection in the vagina to give symptomatic relief.
Gardnerella vaginalis is a microbe highly correlated with bacterial vaginosis and vaginal dysbiosis. G. vaginalis develops biofilms, which can make it treatment-resistant for long periods of time when using conventional treatments.