- Uses glucose
- Related to the bacteria that causes diptheria, Corynebacterium diptheriae
- Found on human skin and mucous membranes as a commensal
- Often disregarded as a contaminant
- Opportunistic pathogen that can cause serious human disease
- First identified in 1988
- Often confused with other pathogens, C. minutissimum and C. xerosis
- Generally resistant to multiple antibiotics
- No standard lab testing
Diseases caused
- Pneumonia
- Peritonitis
- Empyema
- Infectious endocarditis
- Fatal sepsis
Worse infections in those with compromised immune systems. Has been found in human pus, urine, catheter tips, blood, prostatic fluid, spinal fluid, and sputum, and new reports of ear infection.
Drug treatment
Vancomycin or daptomycin has been used in conjunction with rifampicin for four weeks to six months. Infected heart valves may need replacing. No standard treatments due to newness of classification as a pathogen.
Seems sensitive to glycopeptide and lipopeptide antibiotics, but otherwise has broad resistance.
References
- Dalal, Aman; Urban, Segal-Maurer (October 2008). “Endocarditis due to Corynebacterium amycolatum”. Journal of Medical Microbiology. 57 (10): 1299–1302. doi:10.1099/jmm.0.2008/003343-0.
- Knox, Karen. “Nosocomial Endocarditis Caused by Corynebacterium amycolatum and Other Nondiphtheriae Corynebacteria”. Centers for Disease Control and Prevention.
- Belmares, Jaime; Stephanie Detterline; Janet B Pak; Jorge P Parada (2007). “Corynebacterium endocarditis species-specific risk factors and outcomes”. BMC Infectious Diseases. 7: 4. doi:10.1186/1471-2334-7-4. PMC 1804271. PMID 17284316.
- Berner, R; K Pelz; C Wilhelm; A Funke; J U Leititis; M Brandis (April 1997). “Fatal sepsis caused by Corynebacterium amycolatum in premature infant”. Journal of Clinical Microbiology. 35 (4): 1011–1012. PMC 229725. PMID 9157120.
- Koneman, Elmer (2006). Koneman’s Color Atlas and Textbook of Diagnostic Microbiology, 6 ed. Lippincott Williams & Wilkins. p. 798. ISBN 9780781730143.
| Condition type | Bacteria |
|---|---|
| Affected systems | |
| Sexually Transmissible | |
| Genitourinary Incidence | |
| Age group affected |
Microbial information
| Anaerobe / Aerobe | Facultative anaerobe/aerobe |
|---|---|
| Gram stain | Gram-positive |
| Best tests to detect |
|
| Pathogen of |
| Commensal of (Can naturally inhabit, but not necessarily as a healthy addition) |
|
| Optimal growth pH | |
| Conditions correlated with |
|
| Cellular adherence capacities | |
| Found in healthy vaginas | Possibly |
| Biofilm-forming capacities | |
| Cellular Morphology |
|
| Microbe Motility | |
| Colony Colour |
|
| Substances Produced | |
| Sexually Transmissible |
What are the symptoms of Corynebacterium amycolatum vulvovaginal infections?
- No symptoms found for Corynebacterium amycolatum vulvovaginal infections, yet.
What causes Corynebacterium amycolatum vulvovaginal infections?
- No causes found for Corynebacterium amycolatum vulvovaginal infections, yet.
What are the risk factors associated with Corynebacterium amycolatum vulvovaginal infections?
- No risk factors for Corynebacterium amycolatum vulvovaginal infections, yet.
How do you diagnose Corynebacterium amycolatum vulvovaginal infections?
- No diagnoses found for Corynebacterium amycolatum vulvovaginal infections, yet.
How do you treat Corynebacterium amycolatum vulvovaginal infections?
Treatments for Corynebacterium amycolatum vulvovaginal infections are only for practitioners and people who purchased the book Killing BV and Killing BV for men.
Which treatments are likely to be ineffective for Corynebacterium amycolatum vulvovaginal infections?
- No resistances found for Corynebacterium amycolatum vulvovaginal infections, yet.
What complications are associated with Corynebacterium amycolatum vulvovaginal infections?
- No complications found for Corynebacterium amycolatum vulvovaginal infections, yet.
References
Sengupta M, Naina P, Balaji V, Anandan S. Corynebacterium amycolatum: An Unexpected Pathogen in the Ear. J Clin Diagn Res. 2015;9(12):DD01-DD3. doi:10.7860/JCDR/2015/15134.7002 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717710/Yoon S, Kim H, Lee Y, Kim S. Bacteremia caused by Corynebacterium amycolatum with a novel mutation in gyrA gene that confers high-level quinolone resistance. Korean J Lab Med. 2011;31(1):47-48. doi:10.3343/kjlm.2011.31.1.47 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111041/Letek, M., Ordóñez, E., Fernández‐Natal, I., Gil, J. and Mateos, L. (2006), Identification of the emerging skin pathogen Corynebacterium amycolatum using PCR‐amplification of the essential divIVA gene as a target. FEMS Microbiology Letters, 265: 256-263. doi:10.1111/j.1574-6968.2006.00492.x https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1574-6968.2006.00492.x
