Corynebacterium pyruviciproducens in the vagina

Isolated from the human vagina.

May stimulate macrophages, have immunoregulatory properties. Macrophages remove pathogenic bacteria. Promotes antibody response in vivo. Activates macrophages, causes sharp release of interleukin-6 and tumour necrosis factor-α. Promotes host humoral immune response to pathogenic micro-organisms. ​1​

Study on antimicrobial susceptibility​2​

Non-flagellate, non-spore-forming​3​

References

  1. 1.
    Tong J, Han Q, Wang S, et al. Corynebacterium pyruviciproducens, as an immune modulator, can promote the activity of macrophages and up-regulate antibody response to particulate antigen. Exp Biol Med (Maywood). Published online November 2012:1322-1330. doi:10.1258/ebm.2012.012181
  2. 2.
    Goldenberger D, Hinić V, Turan S, et al. Extended Characterization of Corynebacterium pyruviciproducens Based on Clinical Strains from Canada and Switzerland. Diekema DJ, ed. J Clin Microbiol. Published online June 20, 2014:3180-3183. doi:10.1128/jcm.00792-14
  3. 3.
    Qingzhen H, Jia T, Shengjun W, et al. Corynebacterium pyruviciproducens promotes the production of ovalbumin specific antibody via stimulating dendritic cell differentiation and up-regulating Th2 biased immune response. Vaccine. Published online February 2012:1115-1123. doi:10.1016/j.vaccine.2011.12.005
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Jessica Lloyd

Jessica is a degree-qualified naturopath (BHSc) specialising in vulvovaginal health and disease, based in Melbourne, Australia.

Jessica is the owner and lead naturopath of My Vagina, and is a member of the:

  • International Society for the Study of Vulvovaginal Disease (ISSVD)
  • International Society for the Study of Women's Sexual Health (ISSWSH)
  • National Vulvodynia Association (NVA) Australia
  • Australian and New Zealand Vulvovaginal Society (ANZVS)
  • Australian Traditional Medicine Society (ATMS)

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