Finegoldia magna vulvovaginal infections

Finegoldia magna is an opportunistic human pathogen that colonises mucous membranes, the mouth, and the skin. F. magna is often found in biofilms in chronic ulcers, with increasing antibiotic resistance.

F. magna can be found causing infection around the human body, particularly in soft tissue, bones, joints (including prosthetics), heart valves (including prosthetics), wounds, pneumonia, and meningitis, amongst others. F. magna may be found as the sole infectious microbe in an infection, which is unusual, or may be found cohabitating with helpful friends.

One such friend is Staphylococcus aureus, which as a co-infection, can prove tricky to treat. Other commonly found aerobic co-infecters include Streptococcus, S. epidermis, and Escherichia coli. Anaerobes frequently found with F. magna include Prevotella melaninogenica, Bacteroides spp. and B. fragilis.

F. magna is very oxygen-sensitive, so any treatment containing oxygen may work well.

Ferments glucose.

Read more about Finegoldia magna in bacterial vaginosis.

Condition typeBacteria
Affected systemsReproductive, Integumentary, Urinary, Musculoskeletal, Digestive, Cardiovascular, Respiratory
Sexually Transmissible
Genitourinary Incidencecommon
Age group affected
  • birth to death

Microbial information

Anaerobe / AerobeAnaerobe
Gram stainGram-positive
Best tests to detect
  • PCR
  • Culture
Pathogen of
  • Skin
  • Mouth
  • Gut
  • Vagina
  • Urinary tract
Commensal of
(Can naturally inhabit, but not necessarily as a healthy addition)
  • Skin
  • Mouth
  • Gut
  • Vagina
Optimal growth pH
Conditions correlated with
  • Bacterial vaginosis (BV)
  • General human infection
  • Healthy vaginal flora
  • Urinary tract infection (UTI)
  • Vaginal dysbiosis
Cellular adherence capacitiesMedium
Found in healthy vaginasPossibly
Biofilm-forming capacities
  • Medium
Cellular Morphology
  • Coccus (spherical)
Microbe MotilityNon-motile
Colony Colour
  • Whiteish
  • Transparent
Substances Produced
  • Acetic acid (vinegar)
  • Ammonia (ammonia)
Sexually TransmissiblePossibly

What are the symptoms of Finegoldia magna vulvovaginal infections?

What causes Finegoldia magna vulvovaginal infections?

  • No causes found for Finegoldia magna vulvovaginal infections, yet.

What are the risk factors associated with Finegoldia magna vulvovaginal infections?

  • No risk factors for Finegoldia magna vulvovaginal infections, yet.

How do you diagnose Finegoldia magna vulvovaginal infections?

How do you treat Finegoldia magna vulvovaginal infections?

Treatments for Finegoldia magna vulvovaginal infections are only for practitioners and people who purchased the book Killing BV and Killing BV for men.

Which treatments are likely to be ineffective for Finegoldia magna vulvovaginal infections?

What complications are associated with Finegoldia magna vulvovaginal infections?

  • No complications found for Finegoldia magna vulvovaginal infections, yet.

References

Rosenthal et al. 2012. Finegoldia magna (formerly Peptostreptococcus magnus): an overlooked etiology for toxic shock syndrome? Med Hypotheses. 2012 Aug;79(2):138-40. doi: 10.1016/j.mehy.2012.04.013. Epub 2012 May 7. https://www.ncbi.nlm.nih.gov/pubmed/22571938Frick IM, Karlsson C, Mörgelin M, et al. Identification of a novel protein promoting the colonization and survival of Finegoldia magna, a bacterial commensal and opportunistic pathogen. Mol Microbiol. 2008;70(3):695-708. doi:10.1111/j.1365-2958.2008.06439.x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628433/Neumann A, Björck L, Frick IM. Finegoldia magna, an Anaerobic Gram-Positive Bacterium of the Normal Human Microbiota, Induces Inflammation by Activating Neutrophils. Front Microbiol. 2020;11:65. Published 2020 Jan 29. doi:10.3389/fmicb.2020.00065 https://pubmed.ncbi.nlm.nih.gov/32117109/Elizabeth Carmel Murphy, Inga-Maria Frick, Gram-positive anaerobic cocci – commensals and opportunistic pathogens, FEMS Microbiology Reviews, Volume 37, Issue 4, July 2013, Pages 520–553, https://doi.org/10.1111/1574-6976.12005 https://academic.oup.com/femsre/article/37/4/520/2399123Veloo, ACM 2011, 'Gram-positive anaerobic cocci: identification and clinical relevance', Doctor of Philosophy, Groningen. https://www.rug.nl/research/portal/publications/grampositive-anaerobic-cocci(97e8dad8-f635-4d76-95a0-867b24fba468)/export.html https://www.rug.nl/research/portal/files/14500870/08_c8.pdfhttps://catalog.hardydiagnostics.com/cp_prod/Content/hugo/Peptostreptococcus.htmZiółkowska-Klinkosz, M. & Kedzia, A. & Meissner, H.O. & Kedzia, A.W.. (2016). EVALUATION OF THE TEA TREE OIL ACTIVITY TO ANAEROBIC BACTERIA--IN VITRO STUDY. 73. 389-394. http://ptf.content-manager.pl/pub/File/Acta_Poloniae/2016/nr%202/389.pdf

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