M. morganii is a gram negative facultative anaerobic bacillus belonging to the Enterobacteriaceae family.
Morganella morganii is considered an unusual opportunistic pathogen, contributing to post-operative wound1, vaginal2, and urinary tract infections3. M. morganii is resistant to multiple antibiotics (carrying resistance genes blaNDM-1 and qnrD1), posing challenges to infection control.4
M. morganii can cause a variety of infections: sepsis, abscess, purple urine bag syndrome, chorioamnionitis, and cellulitis, and has a high risk profile.
Morganella morganii produces high levels of histamine5, and may contribute to histamine intolerance symptoms in some people.
References6
- 1.Chander J, Singla N, Kaistha N, Gulati N. Morganella morganii could be an important intensive care unit pathogen. Indian Journal of Critical Care Medicine. Published online July 1, 2010:154-155. doi:10.4103/0972-5229.74176
- 2.Srinivasan S, Fredricks DN. The Human Vaginal Bacterial Biota and Bacterial Vaginosis. Interdisciplinary Perspectives on Infectious Diseases. Published online 2008:1-22. doi:10.1155/2008/750479
- 3.Thomas-White K, Forster SC, Kumar N, et al. Culturing of female bladder bacteria reveals an interconnected urogenital microbiota. Nat Commun. Published online April 19, 2018. doi:10.1038/s41467-018-03968-5
- 4.Liu H, Zhu J, Hu Q, Rao X. Morganella morganii, a non-negligent opportunistic pathogen. International Journal of Infectious Diseases. Published online September 2016:10-17. doi:10.1016/j.ijid.2016.07.006
- 5.Pugin B, Barcik W, Westermann P, et al. A wide diversity of bacteria from the human gut produces and degrades biogenic amines. Microbial Ecology in Health and Disease. Published online January 1, 2017:1353881. doi:10.1080/16512235.2017.1353881
- 6.Gameiro I, Botelho T, Martins AI, Henriques R, Lapa P. Morganella morganii: A Rare Cause of Early-Onset Neonatal Sepsis. Cureus. Published online September 20, 2023. doi:10.7759/cureus.45600
