Porphyromonas gingivalis vulvovaginal infections

Porphyromonas gingivalis is a prolific pathogen that is found mostly in the mouth, where it can cause some forms of periodontal disease. P. gingivalis has also been found in the digestive tract, respiratory tract, and in some women with bacterial vaginosis.

This species produces collagenase, which breaks down collagen, allowing the bacteria to enter skin cells, surviving even high doses of antibiotics.

P. gingivalis may contribute to conception issues in women. Lactobacillus gasseri, one of the possible major friendly microbes involved in a healthy vagina, was demonstrated in a mouse model to improve oral symptoms of periodontal disease and bone loss when P. gingivalis was present, offering an option for oral and vaginal dosing to clear P. gingivalis.

Condition typeBacteria
Affected systemsReproductive, Digestive
Sexually Transmissible
Genitourinary Incidencemoderate
Age group affected

Microbial information

Anaerobe / AerobeAnaerobe
Gram stainGram-negative
Best tests to detect
Pathogen of
Commensal of
(Can naturally inhabit, but not necessarily as a healthy addition)
Optimal growth pH
Conditions correlated with
Cellular adherence capacities
Found in healthy vaginas
Biofilm-forming capacities
  • Shares biofilms
Cellular Morphology
  • Bacillus (rod-shaped)
Microbe Motility
Colony Colour
Substances Produced
Sexually Transmissible

What are the symptoms of Porphyromonas gingivalis vulvovaginal infections?

What causes Porphyromonas gingivalis vulvovaginal infections?

  • No causes found for Porphyromonas gingivalis vulvovaginal infections, yet.

What are the risk factors associated with Porphyromonas gingivalis vulvovaginal infections?

  • No risk factors for Porphyromonas gingivalis vulvovaginal infections, yet.

How do you diagnose Porphyromonas gingivalis vulvovaginal infections?

  • No diagnoses found for Porphyromonas gingivalis vulvovaginal infections, yet.

How do you treat Porphyromonas gingivalis vulvovaginal infections?

Treatments for Porphyromonas gingivalis vulvovaginal infections are only for practitioners and people who purchased the book Killing BV and Killing BV for men.

Which treatments are likely to be ineffective for Porphyromonas gingivalis vulvovaginal infections?

What complications are associated with Porphyromonas gingivalis vulvovaginal infections?

  • No complications found for Porphyromonas gingivalis vulvovaginal infections, yet.

References

Porphyromonas gingivalis: An invasive and evasive opportunistic oral pathogen. FEMS Microbiology Letters, 333(1), pp.1–9, https://academic.oup.com/femsle/article/333/1/1/586464Kobayashi, R. et al., 2017. Oral administration of Lactobacillus gasseri SBT2055 is effective in preventing Porphyromonas gingivalis-accelerated periodontal disease. Scientific Reports, 7(1), pp.1–10, https://www.nature.com/articles/s41598-017-00623-9León, R. et al., 2007. Detection of Porphyromonas gingivalis in the Amniotic Fluid in Pregnant Women With a Diagnosis of Threatened Premature Labor. Journal of Periodontology, 78(7), pp.1249–1255, http://www.joponline.org/doi/10.1902/jop.2007.060368Paju, S. et al., 2017. Porphyromonas gingivalis may interfere with conception in women. Journal of Oral Microbiology, 9(1), p.1330644, https://www.tandfonline.com/doi/full/10.1080/20002297.2017.1330644Persson, R. et al., 2009. The vaginal microflora in relation to gingivitis. BMC Infectious Diseases, 9, pp.1–8, https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-9-6

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