Prevotella bivia in the vagina

Prevotella bivia is found in many human infections, including the vagina and reproductive tract, where it is known to contribute to bacterial vaginosis^​1–3​ and pelvic inflammatory disease. P. bivia may also be found in healthy samples from the female reproductive tract and other areas of the body, such as the mouth.

P. bivia has been found in infected uterine and placental tissue and amniotic fluid during pregnancy complications, with colonisation correlated with increased risk of preterm birth.

In vitro studies may indicate a growth partnership between Gardnerella vaginalis and P. bivia using ammonia^​4​. P. bivia produces ammonia, while G. vaginalis utilises ammonia.

Peptostreptococcus anaerobius may proliferate in the presence of P. bivia^​1​. 

P. bivia is oxygen-sensitive, thus any treatment containing oxygen may be successful. P. bivia, however, is not likely to be the only issue in the vagina during vaginal dysbiosis.

Possible early indicator of BV, works well in a team of other pathogens. Odour likely to be ammonia^​5​. Can spread to uterus, becoming dangerous during pregnancy. ^​6​

Relationship to human papillomavirus (HPV) when found in high numbers. May enter cervical cells, causing inflammation, being undetected by your immune system at times^​8​.

References