Saccharomyces cerevisiae is a yeast that can inhabit the vagina, but is most famous for fermentation in wine, baking bread and brewing beer. Vulvovaginitis – inflammation, itching, and discharge – caused by this yeast is uncommon, but does occur. It is likely to occur more in women who work around these yeasts (or are in a relationship with someone who does), particularly in a bakery or brewery.
Saccharomyces cerevisiae is closely related to Candida glabrata, a common vulvovaginitis-causing yeast, sharing many characteristics with this yeast. Mucosal surfaces like the vagina can become infected with Saccharomyces cerevisiae, particularly with previous exposure to fluconazole, to which this yeast is resistant. Greater infections are likely to be seen with Saccharomyces cerevisiae in future, due to antifungal resistance.
Antibodies to S. cerevisiae are found in 60-70 per cent of people with Crohn’s disease compared with eight per cent of healthy people.
Saccharomyces cerevisiae may also be referred to as Candida robusta.
