Pediococcus acidilactici is a lactic-acid producing bacteria typically found in the human digestive tract as a beneficial commensal1. P. acidilactici is considered a probiotic bacteria2.
P. acidilactici has good adherence qualities to epithelial cells and exhibits antimicrobial activity against some gram-positive and gram-negative pathogens such as Listeria monocytgenes, Salmonella enterica, Shigella sonnei, Klebsiella oxytoca, Enterobacter cloacae and Streptococcus pyogenes1.
P. acidilactici does not cause rupture of red blood cells (haemolysis) or degradation of proteins using proteinase (trypsin), while producing acid.
P. acidilactici has been studied across multiple platforms, from multiple sclerosis research to food science.3
- Grows in a range of pH, temperature and osmotic pressure4
- Colonises the digestive tract4
- Commonly found in fermented vegetables, fermented dairy products, and meat5
- Viable at very low pH, but grows best at a pH of 6.2
- Antagonistic against other microorganisms including pathogens via secretion of lactic acid and bacteriocins (peidocins)6
Beneficial qualities of P. acidilactici
- Probiotic used to treat constipation and diarrhoea, stress, and enhancing immune responses in birds and small animals
- Human trials are still limited, but P. acidilactici prevents small intestinal colonisation of pathogens in small animals
- Dogs with digestive problems have been treated with P. acidilactici and Saccharomyces bouldardii for parvovirus, and after vomiting and bloody diarrhoea, three days’ treatment saw the dogs with solid stools
- Normalises dogs’ intestinal microflora after antibiotic therapy, when taken with antibiotics
- No known toxic effects
References
- 1.Abbasiliasi S, Tan JS, Bashokouh F, et al. In vitro assessment of Pediococcus acidilactici Kp10 for its potential use in the food industry. BMC Microbiol. Published online May 23, 2017. doi:10.1186/s12866-017-1000-z
- 2.Othman M, Ariff AB, Kapri MR, Rios-Solis L, Halim M. Growth Enhancement of Probiotic Pediococcus acidilactici by Extractive Fermentation of Lactic Acid Exploiting Anion-Exchange Resin. Front Microbiol. Published online October 29, 2018. doi:10.3389/fmicb.2018.02554
- 3.Takata K, Kinoshita M, Okuno T, et al. The Lactic Acid Bacterium Pediococcus acidilactici Suppresses Autoimmune Encephalomyelitis by Inducing IL-10-Producing Regulatory T Cells. Ashour HM, ed. PLoS ONE. Published online November 15, 2011:e27644. doi:10.1371/journal.pone.0027644
- 4.Klaenhammer T. Genetics of bacteriocins produced by lactic acid bacteria. FEMS Microbiology Reviews. Published online September 1993:39-85. doi:10.1016/0168-6445(93)90057-g
- 5.Barros RR, Carvalho MDGS, Peralta JM, Facklam RR, Teixeira LM. Phenotypic and Genotypic Characterization of Pediococcus Strains Isolated from Human Clinical Sources. Journal of Clinical Microbiology. Published online April 1, 2001:1241-1246. doi:10.1128/jcm.39.4.1241-1246.2001
- 6.Daeschel MA, Klaenhammer TR. Association of a 13.6-Megadalton Plasmid in Pediococcus pentosaceus with Bacteriocin Activity †. Applied and Environmental Microbiology. Published online 1985:1538-1541. doi:10.1128/aem.50.6.1538-1541.1985
| Condition type | Bacteria |
|---|---|
| Affected systems | Reproductive, Digestive, Respiratory |
| Sexually Transmissible | |
| Genitourinary Incidence | moderate |
| Age group affected |
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Microbial information
| Anaerobe / Aerobe | Facultative anaerobe/aerobe |
|---|---|
| Gram stain | Gram-positive |
| Best tests to detect |
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| Pathogen of | Commensal of (Can naturally inhabit, but not necessarily as a healthy addition) |
|
| Optimal growth pH |
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| Conditions correlated with | |
| Cellular adherence capacities | High |
| Found in healthy vaginas | Possibly |
| Biofilm-forming capacities | |
| Cellular Morphology |
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| Microbe Motility | |
| Colony Colour | |
| Substances Produced | |
| Sexually Transmissible | Possibly |
What are the symptoms of Pediococcus acidilactici in the vagina?
- No symptoms found for Pediococcus acidilactici in the vagina, yet.
What causes Pediococcus acidilactici in the vagina?
- No causes found for Pediococcus acidilactici in the vagina, yet.
What are the risk factors associated with Pediococcus acidilactici in the vagina?
- No risk factors for Pediococcus acidilactici in the vagina, yet.
How do you diagnose Pediococcus acidilactici in the vagina?
- No diagnoses found for Pediococcus acidilactici in the vagina, yet.
How do you treat Pediococcus acidilactici in the vagina?
Treatments for Pediococcus acidilactici in the vagina are only for practitioners and people who purchased the book Killing BV and Killing BV for men.
Which treatments are likely to be ineffective for Pediococcus acidilactici in the vagina?
- No resistances found for Pediococcus acidilactici in the vagina, yet.
What complications are associated with Pediococcus acidilactici in the vagina?
- No complications found for Pediococcus acidilactici in the vagina, yet.