Staphylococcus lugdunensis in the urogenital tract

Staphylococcus lugdunensis is not a common infectious agent, being generally considered to be a commensal of the skin​1​.

What we know:

  • Atypical in its virulence factors​2​
  • Unique microbial profile
  • May be misidentified as Staphylococcus aureus
  • Causes abscesses and wound infections of skin and soft tissue, particularly around implanted devices such as catheters
  • Cause of urinary tract infection
  • Shares antimicrobial susceptibility and resistance with S. aureus
  • Binds and interacts with host cells
  • Builds biofilms on host tissue and artificial surfaces
  • Can clot plasma – coagulase-negative staphylococci (CNS)

References

  1. 1.
    Heldt Manica LA, Cohen PR. Staphylococcus lugdunensis Infections of the Skin and Soft Tissue: A Case Series and Review. Dermatol Ther (Heidelb). Published online October 11, 2017:555-562. doi:10.1007/s13555-017-0202-5
  2. 2.
    Frank KL, del Pozo JL, Patel R. From Clinical Microbiology to Infection Pathogenesis: How Daring To Be Different Works for            Staphylococcus lugdunensis. Clin Microbiol Rev. Published online January 2008:111-133. doi:10.1128/cmr.00036-07
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