Ureaplasma urealyticum vulvovaginal infections

Effect on vaginal cells – inflammatory, can cause urethritis, may be commensal.

Possible ammonia odour – urease positive.

Genital Mycoplasmas include:

Both types cause inflammation. U. parvum, and possibly U. urealyticum, are associated with preterm birth​1,2​. U. urealyticum is linked with male infertility​3,4​ and bacterial vaginosis (BV), with that effect increasing with the joint efforts of U. parvum​5​.

Ureaplasma species can form biofilms (in vitro at least), with biofilms strengthening antibiotic resistance​6​.

References

  1. 1.
    Sobouti B, Fallah S, Mobayen M, Noorbakhsh S, Ghavami Y. Colonization of Mycoplasma hominis and Ureaplasma urealyticum in pregnant women and their transmission to offspring. Iran J Microbiol. 2014;6(4):219-224. https://www.ncbi.nlm.nih.gov/pubmed/25802703
  2. 2.
    Tristram D. Maternal Genital Tract Infection. In: Mucosal Immunology. Elsevier; 2015:2215-2229. doi:10.1016/b978-0-12-415847-4.00113-0
  3. 3.
    Simón Rodríguez C, Charry Gónima P, García Cardoso JV, González Enguita C. Infectious and Inflammatory Male Infertility. In: Encyclopedia of Reproduction. Elsevier; 2018:291-296. doi:10.1016/b978-0-12-801238-3.64546-4
  4. 4.
    Zhou YH, Ma HX, Shi XX, Liu Y. Ureaplasma spp. in male infertility and its relationship with semen quality and seminal plasma components. Journal of Microbiology, Immunology and Infection. Published online December 2018:778-783. doi:10.1016/j.jmii.2016.09.004
  5. 5.
    Frølund M, Falk L, Ahrens P, Jensen JS. Detection of ureaplasmas and bacterial vaginosis associated bacteria and their association with non-gonococcal urethritis in men. Fredricks DN, ed. PLoS ONE. Published online April 4, 2019:e0214425. doi:10.1371/journal.pone.0214425
  6. 6.
    Pandelidis K, McCarthy A, Chesko KL, Viscardi RM. Role of Biofilm Formation in Ureaplasma Antibiotic Susceptibility and Development of Bronchopulmonary Dysplasia in Preterm Neonates. The Pediatric Infectious Disease Journal. Published online April 2013:394-398. doi:10.1097/inf.0b013e3182791ae0
Condition typeBacteria
Affected systemsReproductive, Urinary
Sexually Transmissibleyes
Genitourinary Incidencevery common
Age group affected
  • puberty onward

Microbial information

Anaerobe / AerobeAerobe
Gram stainGram-negative
Best tests to detect
  • PCR
Pathogen of
  • Vagina
  • Urinary tract
Commensal of
(Can naturally inhabit, but not necessarily as a healthy addition)
  • Vagina
  • Urinary tract
Optimal growth pH
  • 6
  • 6.5
Conditions correlated with
  • Bacterial vaginosis (BV)
  • General human infection
  • Sexually transmitted infection (STI)
  • Urinary tract infection (UTI)
  • Vaginal dysbiosis
Cellular adherence capacitiesHigh
Found in healthy vaginasPossibly
Biofilm-forming capacities
  • High
Cellular Morphology
  • Pleomorphic (many shapes)
Microbe MotilityNon-motile
Colony Colour
Substances Produced
Sexually TransmissibleYes

What are the symptoms of Ureaplasma urealyticum vulvovaginal infections?

What causes Ureaplasma urealyticum vulvovaginal infections?

  • No causes found for Ureaplasma urealyticum vulvovaginal infections, yet.

What are the risk factors associated with Ureaplasma urealyticum vulvovaginal infections?

  • No risk factors for Ureaplasma urealyticum vulvovaginal infections, yet.

How do you diagnose Ureaplasma urealyticum vulvovaginal infections?

  • No diagnoses found for Ureaplasma urealyticum vulvovaginal infections, yet.

How do you treat Ureaplasma urealyticum vulvovaginal infections?

Treatments for Ureaplasma urealyticum vulvovaginal infections are only for practitioners and people who purchased the book Killing BV and Killing BV for men.

Which treatments are likely to be ineffective for Ureaplasma urealyticum vulvovaginal infections?

What complications are associated with Ureaplasma urealyticum vulvovaginal infections?

References

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