Lichen sclerosus clinical trials in progress or recruiting

Check out current clinical trials for lichen sclerosus being undertaken across the world.

Urethritis

Urethritis simply means inflammation of the urethra, and has many causes, but the most common is a urinary tract infection. Classic symptoms include burning while you urinate, urgency and frequency.

Vulvar intraepithelial neoplasia (VIN) (SIL, Bowen disease)

We explain what precancerous vulvar cells are, and describe their symptoms, treatments, and outcomes. Vulval intraepithelial neoplasia (VIN) is the starting point of cancerous cells, with a diagnosis meaning you may have to have some treatment to remove the offending cells. It does not mean you have cancer.

Urethral prolapse

Urethral prolapse is an uncommon condition that is treatable in most cases, with very good outcomes. The urethra or part of the sleeve of the urethra protrudes out, causing discomfort and urinary issues.

Marsupialisation of a Bartholin (vestibular) gland cyst

This surgery involves cutting open a Bartholin's duct cyst, and suturing the walls to allow draining.

Marsupialisation of a vaginal cyst

Marsupialisation is a surgical technique whereby a slit is cut into an cyst and the edges are sewn onto other skin to keep it open.

Gartner’s duct cysts

Gartner's duct cysts are caused by a duct that should no longer exist after we are born, that causes a cyst to develop inside the vagina.

Ureterocele

Ureteroceles are a birth defect affecting the ureters, resulting in problems with urine flow. The connection point of the bladder and lower ureters becomes swollen, and urine flow is blocked, causing the ureters to expand like a water balloon.

Cancer treatments

Vaginal, vulvar and pelvic cancer therapies depend on the type, spread and stage of cancerous growths. Treatments for early stage cancer may include simply removing the cancer, but may involve invasive or cell-damaging treatments like chemotherapy or radiotherapy.

Paget’s disease of the vulva

Paget's disease of the vulva is a rare form of vulvar cancer that develops from glandular cells. Paget's looks like a rash, red velvet with small white or pink 'islands' on vulvar tissue that may ooze or bleed. Paget's is often itchy and sore. Prognosis can be good if found

Study: Replens – a review for BV symptoms and vaginal pH (spoiler – it doesn’t work that well)

Replens does not significantly alter vaginal pH, and is not a treatment for BV, however may improve some symptoms.

Undestanding and treating cytolytic vaginosis (CV) (lactobacillus overgrowth syndrome)

Cytolytic vaginosis is a condition of problematic lactobaillus overgrowth, typically L. crispatus, causing burning and irritation.

Skoptic syndrome – genital self-mutilation

Why would someone want to cut their own genitals off? Skoptic syndrome is a part of psychological impairments whereby the urge to cut off one's own genitals is very strong.

Gishiri cutting

Gishiri cutting is a form of genital mutilation that involves cutting down the back wall of the vagina.

FGM/cutting and genital modifications

A brief description of female genital mutilations and modifications.

Congenital adrenal hyperplasia (CAH)

Congenital adrenal hyperplasia (CAH) is an adrenal gland disorder where the production of cortisol is affected by an enzyme defect. Androgen precursors accumulate in the blood, with results that range from salt-wasting, high blood pressure, and virilising/feminising.

Clitoridectomy

Clitoridectomy is the complete or partial removal of the clitoris, which may be a course of action it the clitoris is oversized and the owner makes the big decision to part with it.

The practice of labial stretching

Labia stretching is a common practice amongst some African women, and is said to improve squirting abilities.

The Prader Scale of genitalia explained

The Prader Scale shows human genitalia from 0 to 6, from typically female at one end to typically male.

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