Some bacteria excrete such enzymes, with a certain glycosidase involved being sialidase, which is frequently associated with BV organisms. A synergistic enzymatic activity may exist between bacteria in BV to take control of the vagina. The bacteria do this by dissolving the mucosal barrier and adhering to the vaginal cells, though we’re not sure exactly how this process works specifically. What we do know is that bacterial mesogens may play a significant role in the colonisation of BV bacteria.
This research looked into whether glycosulfatase – a mucolytic enzyme – targeted towards sulfated oligosaccharide side chains is also associated with BV. Glycosulfatases work like this in the digestive tract.
Sixty-one women between the ages of 16 to 50 years were studied. Thirty-one were graded as having no BV (grade I), four had intermediate flora (grade II), and 24 were graded as having BV (grade III). Two were later excluded from the study.