The Centers for Vulvovaginal Disorders in the US has hypothesised that the oral contraceptive pill causes vulvodynia by causing changes to the hormone receptors in the vulvar vestibular mucosa.
Thinning may occur in the vulvar vestibule causing possible genetic changes in the androgen receptors – it might be possible to predict which women will develop vulvodynia. This study is now closed to new participants.

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