Review: Klaire Labs InterFase and InterFase Plus

Klaire Labs has developed InterFase and InterFase Plus to break down pathogenic biofilms in the digestive tract, while sparing many healthy biofilms.

Biofilms can alter the intestinal environment making it difficult or impossible for other beneficial species to get a foothold and develop healthy biofilms.

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Healthy bacterial biofilms preserved by InterFase Plus include those of:

  • Bifidobacterium bifidum PT131
  • Bifidobacterium breve PT132
  • Bifidobacterium longum PT136
  • Lactobacillus casei PT116
  • Lactobacillus rhamnosus PT112
  • Lactobacillus salivarius ATCC 29602

Pathogenic bacterial biofilms disrupted include those of:

How does InterFase work?

InterFase and InterFase Plus have a multitude of enzymes demonstrated in the lab to break down bacterial biofilms from a range of bacteria and fungi, including Candida albicans and Gardnerella vaginalis.

Biofilms require calcium, iron and magnesium to develop, and InterFase Plus includes a special acid (EDTA) that binds the metals, removing them from available resources of the bacteria. Binding interrupts the biofilm creation process.

Iron-deficiency anaemia and InterFase Plus

This binding process interrupts pathogenic bacterial ability to create a biofilm, but could also cause a problem for those who are already suffering low iron.

Many pathogens use iron from our food and can be a trigger for iron-deficient anaemia. Talk to your doctor if this applies to you.

The process could be a bit hard on your body, so care needs to be taken.

How to take InterFase and InterFase Plus

InterFase and InterFase plus are used to support normal gastrointestinal flora and gut function and are best used with a broad, multispecies probiotic formulation and a prebiotic to support normal, healthy colonies and biofilms in the intestine.

InterFase products can be used with other antimicrobials (like antibiotics or herbs).

Dose of InterFase or InterFase Plus

  • Take 1-4 capsules of InterFase or 2-8 capsules of InterFase Plus daily, dependent on age and size
  • See the packet insert for instructions
  • Take away from meals for maximum impact

Dose: 2 capsules, 60 or 120 caps per container

Cost: InterFase and InterFase Plus are about US$20-$40 per 120 capsules online, but the price seems to vary depending on your location

Who can’t take InterFase or InterFase Plus?

Anyone with an egg white allergy should speak to their doctor before taking this product.

InterFase Ingredients (500mg – 2 capsules)

  • Glucoamylase (with isomaltase side chain activity)
  • Chitosanase
  • Cellulase
  • Hemicellulase/Pectinase Complex
  • Beta-Glucanase
  • Protease/Peptidase Complex with endopeptidase, exopeptidase, and DPP-IV activity
  • Lysozyme (from egg white)
  • Serratia peptidase (enteric-coated)

InterFase Plus Ingredients (750mg 2 capsules)

  • Glucoamylase (with isomaltase side chain activity)
  • Chitosanase
  • Cellulase
  • Hemicellulase/Pectinase Complex
  • Beta-Glucanase
  • Protease/Peptidase Complex with endopeptidase, exopeptidase, and DPP-IV activity
  • Lysozyme (from egg white)
  • Serratia peptidase (enteric-coated)
  • EDTA (as disodium EDTA)

Other ingredients:

  • Vegetable caps (hydroxypropyl methylcellulose, water)
  • L-leucine, and cellulose

Does this product work in the vagina?

InterFase is designed to be taken orally and ingested. The enzyme product works throughout your digestive tract but is not absorbed into the bloodstream.

InterFase cannot directly reach the vagina unless used as a douche.

Do not insert InterFase capsules into the vagina, as it is likely to cause irritation.

Safety and side-effects

Some people have unpleasant side-effects after taking this product.

Everyone is different, so start off slow, follow all the instructions, and get help from a doctor or other healthcare practitioner if you aren’t sure how the treatment will impact you.

If you are pregnant, talk to your healthcare practitioner first.

Some listed side-effects have included migraines, intestinal upsets, and flu-like symptoms, which could be due to the biofilm disintegration releasing trapped microbes into your system.

For more information on this product, see the Klaire Labs manufacturer’s factsheet (PDF).



Original price was: USD $9.95.Current price is: USD $0.00. ex GST/VAT/TAX
Original price was: USD $9.99.Current price is: USD $0.00. ex GST/VAT/TAX
Jessica Lloyd - Vulvovaginal Specialist Naturopathic Practitioner, BHSc(N)

Jessica is a degree-qualified naturopath (BHSc) specialising in vulvovaginal health and disease, based in Melbourne, Australia.

Jessica is the owner and lead naturopath of My Vagina, and is a member of the:

  • International Society for the Study of Vulvovaginal Disease (ISSVD)
  • International Society for the Study of Women's Sexual Health (ISSWSH)
  • National Vulvodynia Association (NVA) Australia
  • New Zealand Vulvovaginal Society (ANZVS)
  • Australian Traditional Medicine Society (ATMS)
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